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FPID can be used to synthesize dipeptides from various standard amino acids, including sterically hindered amino acids, and the pentapeptide leu-enkephalin in protected form. It also can be used to the solid-phase peptide synthesis
参考文献：
[1] Liu, S.; Sun, B.; Tian, J.; Zhang, C. Practical Peptide Synthesis Mediated by a Recyclable Hypervalent Iodine Reagent and Tris(4-methoxyphenyl)phosphine. Org. Lett. 2015, 17
Recyclable hypervalent-iodine-mediated solid-phase peptide synthesis and cyclic peptide synthesis. Beilstein J. Org. Chem. 2018, 14, 1112–1119. |
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